From Charlotte
- Start on I-85 N toward Greensboro
- Merge into Bus 85, toward Lexington/High Point/Winston-Salem
- Merge onto I-85 BL N/ I-85 BR N toward High Point
- Take the NC-8 N exit toward Winston-Salem
- Turn LEFT onto NC-8/ Salem Street, Continue to follow NC-8
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From Winston-Salem
- Start on US-52 South
- Take the NC-8 exit
- Turn LEFT onto NC-8/ OLD US-52, Continue to follow NC-8
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From Greensboro
- Start I-85 S toward High Point/Charlotte
- Take the US-64 exit- exit number 96- toward Asheboro/Lexington
- Merge onto I-85 BL S/ US-64 W/ I-85 BR S
- Take the NC-8 exit
- Turn right onto NC-8
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From Statesville
- Start on I-40 East
- Take the US-64 exit- exit number 168 then turn Right onto 64
- Turn LEFT onto US-64/ US-601/ Salisbury Street, Continue to follow US-64 E
- Take the NC-8 N exit toward Winston-Salem
- Turn LEFT onto NC-8/ Salem Street, Continue to follow NC-8
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From High Point
- Start on I-85 BL S/ I-85 BR S
- Take the NC-8 exit
- Turn right onto NC-8
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From Salisbury
- Start on I-85 N
- Take the I-85-BR exit- exit number 87- toward
Lexington/High Point/Winston-Salem
- Take the I-85-BR exit- exit number 87- toward High Point
- Take the NC-8 N exit toward Winston-Salem
- Turn LEFT onto NC-8/ Salem Street, Continue to follow NC-8
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